Handling what gracefully? This is an avast support forum. Vista will be the next popular OS from MS. What's to handle? People will come for help and they will get it. Win95, 98, 98SE, 98ME, Win2000 and XP users all get the same support here. Why would there be a need to do it any other way with Vista users? Alwil seems to be handling Vista just fine. And indeed they need to work along side those "Puppet Masters" to remain competitive and receive max possible market exposure.
I recall many moaning about XP before it came out. It is a much greater improvement over 98 though. Without growth there is stagnation. Growth is change. Some will be happy with current solutions and some will not.