If a virus is replicant (coming and coming again) or you can't delete it (file in use), you should:
1) Enable/Disable System restore on
Windows ME or
Windows XP. System Restore cannot be disabled on Windows 9x and it's not available in Windows 2k.
2) Clean your temporary files. You can use the
Windows Advanced Care features for that.
3) Schedule a boot time scanning with avast. Start avast! > Right click the skin > Schedule a boot-time scanning. Select for scanning archives. Boot. Other option is scanning in
SafeMode (repeatedly press F8 while booting).
4) It will be good if you download, install, update and run other trojan remover tools:
a-squared,
Free AVG Antispyware or
SUPERantispyware (trojan removers). Some users recommend
Spyware Terminator.
5) Use the immunization of
Windows Advanced Care features of spyware/adware cleaning and removal.
Hope it helps. Welcome to forums.