Personally, if these broken Registries were causing you actual problems you should be seeing windows errors.
Just looking at the various headings in the list, I don't see any there that I would consider serious. Also, given the titles I don't see any that resolving them would see any great improvement.
Personally I don't run any on-demand scans (outside of questions in the forums) as Avast is an on-access program, which should be scanning active files. Dormant files don't present an immediate risk, when they become active Avast would scan them.
With a resident (on-access) scanner the need for on-demand scans is much depreciated. For the most part dormant/inert files are being scanned, the other active files are going to be scanned by the resident shields when they are activated.