Personally as a first step I would rename it so whatever is running it won't find the original file and may just pop-up the file not found message and see if there is any way to get a handle on it.
If with it renamed if it isn't causing any issues and I don't believe it should then I would add it to the avast chest User Files section (so you always have a fall back option) before deleting it in the system32 folder.