it could be a new variant of Win32:Beagle... send the sample to virus[at]avast[dot]com.. can you list the recently changed files on the infected HDD from the other machine? most interesting is the windows folder, system32 subfolder, system32\drivers and maybe a root of the drive..
OK, I sent the file to
http://virusscan.jotti.org/ and it tells:
File: setup.exe
Status: INFECTED/MALWARE (Note: this file has been scanned before. Therefore, this file's scan results will not be stored in the database)
MD5: 7273363da6c59b96dad6616a37d25d97
Packers detected: -
-------------
A-Squared Found Trojan-Downloader.Win32.Bagle!IK
AntiVir Found TR/Dldr.Bagle.aha
ArcaVir Found nothing
Avast Found nothing
AVG Antivirus Found Win32/Themida
BitDefender Found DeepScan:Generic.Bagle.9D1F90F4
ClamAV Found nothing
CPsecure Found nothing
Dr.Web Found Trojan.Packed.650
F-Prot Antivirus Found nothing
F-Secure Anti-Virus Found Trojan-Downloader.Win32.Bagle.aha
G DATA Found DeepScan:Generic.Bagle.9D1F90F4
Ikarus Found nothing
Kaspersky Anti-Virus Found Trojan-Downloader.Win32.Bagle.aha
NOD32 Found nothing
Norman Virus Control Found nothing
Panda Antivirus Found nothing
Sophos Antivirus Found Mal/Bagle-B
VirusBuster Found nothing
VBA32 Found nothing
So it looks like Bagle in fact. I've sent you the infector file (subject of mail is: Virus bagle stops the Avast antivirus)