I've been trialling Avast Pro on one computer, and I like the script blocker function.
All other computers run Avast Home. I have USB wireless modem, only work single computer at a time, no network, so run standalone computers, different internet at different times, all have same web connect, and basically same desktop platform (XP Home or Pro), same exposure and protections, resident Avast shield at startup, add range of anti-malware when want / need, don't go there when warned not to, and no worthwhile false postives to talk about since last year.
No bottom-line difference between Avast Home and Pro to date.
But this may depend on the nature of your workload. If you are professional IT environment, then preferable to work with Pro, which is design for more technical types (record and research and retrieve or reset exposure and protections). Some IT wont load Avast Home only because they need be protected from adverse user behavioral, so Pro with after-sales service is good option for them. But yet to find one that says Avast Home is any lesser effective.
My rule is for home user who is worried about whether their workload means too big exposure for Home to cover, then they should go Pro. Also, if they can afford Pro, then go Pro. That said, my workload and exposure is big and yet I find Avast Home ideal. Granted I also protect against host file intrusion and protect against spyware and the like. All the protections I use can be found in Avast forum.
By running Avast Home I can keep abreast of what picture my people see on their screen and understand what problem they are talking about. Some know Avast, others can barely use MSWord, one only uses the web to bet electronically on the horse races. None of them get viruses anymore, not since they brought their infected PCs around to be fixed. I believe I have had a few brushes with malware, that might have led to infection, but then you would expect that with my exposure.
Trial time is up soon, and I might buy Pro this time around. Since there is work being lined up which may require more depth IT monitor and maintain. With larger external party, extra conditions to consider.
But otherwise, Avast Home seems adequate for computer user.