I seriously thought my computer was infected last night with DELF-MZG adn Zbot-MKK and allowed Avast to delete the reported infected executables. (Adbobe, Nero, and many more of my programs) When it got to some infections in my Win32 folder, I was expecting post boot problems and sure enough, my computer will not get past the BIOS post now.
I'll be trying a Windows repair install today and if successful a re-install of the now damaged programs.
I'm only posting this as FYI as to the possible impact of this problem on other users.