Yesterday I had the same problem. And "Mozillla firefox" didn´t go to virustotal.com, when I told it to, but to some random infected website.
I have manually identified and solved the problem (Seeked and deleted the virus "manually" without antivirus).
I used "Sysinternals Process Monitor" to find the malware that was creating those files. It was
C:\Documents and Settings\usuario\Configuración local\Temp\0.9435061735453691.exe
I deleted the file (and saved a copy for later inspection). The file is detected as virus/trojan by several antivirus in virustotal and virusscan.jotti.org
I rebooted the system, and the problem persisted.
Again with Process monitor, I found the program that was recreating "0.9435061735453691.exe" which in turn created 1.exe, 4.exe ...
The root of the problem was
c:\windows\system32\qtplugin.exe
I needed the utility tool "unlocker" to delete it ("on next boot"), as it couldn´t be deleted by windows explorer.
THIS IS NOT DETECTED AS VIRUS by virusscan.jotti.org, Only one (prevx) of the 41 antivirus in virustotal detects it. But it IS a virus for sure.
Both 0.9435061735453691.exe and qtplugin.exe where in several keys in windows register that I have manually removed.
I have a copy of the new virus qtplugin.exe and of the other one "0.9435061735453691.exe", just in case someone in avast! wants it. I just don´t know where to report it.
Regards