What other security software do you have on your machine...currently and previously?
What is your current firewall (FW)? Did you check to see if it was blocking Avast?
What version of Avast do you have installed, and was this is upgrade or a clean/new install? How long have you had this on your machine?
What is your OS, RAM, CPU, what browser do you use? If you use add-on's, please list them.