The boot-time scan as suggested by Tech should be able to get round the access denied error.
Though a google search seems to indicate the detection is good, it wouldn't hurt to confirm the detection:
You could also check the offending/suspect file at:
VirusTotal - Multi engine on-line virus scanner and
report the findings here the URL in the Address bar of the VT results page. You can't do this with the file securely in the chest, you need to extract it to a temporary (not original) location first, see below.
Create a folder called
Suspect in the
C:\ drive. Now exclude that folder in the
File System Shield, Expert Settings, Exclusions, Add, type (or copy and paste)
C:\Suspect\* That will stop the File System Shield scanning any file you put in that folder.