Not a 'computer' HIPS fan here
I use computer to 'enjoy' my time, to make my works 'easier' and deal with fewer stuff to do something.
A HIPS protection is something that avoid that, like I don't like answer a lot of questions to run a new program and start working, or answer a bunch of question to watch a DVD...
Really I see no reason to use HIPS. If my computer is web-client, Well, Sandbox will do the job! or an Installation of Ubuntu inside windows is something really easy. if my computer is developing station so HIPS is toxin for such system and only a silent firewall and an AV with very high-detetion rate is fine since only experts are using that system. if system is for average users who want to play online game, watch movie, run games got from friends etc. HIPS will not works because they will keep allowing to start the stuff so again HIPS became useless...
there are very few users who could got a real benefit from HIPS. because I could infect systems protected with HIPS. HIPS will prevent what I said in beginning. you use security software to don't get adware popup and instead HIPS will give you popup, you use security software to don't let malware slow-down your computer and instead HIPS will slowdown your works with eat resource or ask question before everything....
one other thing is that else than 1-2 HIPS enabled products almost every other HIPS products had a lot of bug or compability problems.
(tonight I've a lot of typo because my Google Chrome Spell-checker does not work!) [1:55 AM here!]