Hi thanks for the advice, but have come to a stumbling block.
I ran the process through OTL, and then did a quick scan (will attach the log later as at work now), downloaded Combofix, but when I run it, i get the following error pop up.
3278SR22FWJFW/Iexplore.exe
Windows cannot access the specified path or file
and that repeats about a dozen times then comes up with the same message for a few other files.
Not sure if its relevant, but have started getting notifications for Ramnit B as well... Also had to re-download OTL before I fan your script as avast quarantined it...
Will attach the logs when I get home this PM.
Thanks,
Gaz