Yesterday I downloaded and installed the new Spybot Beta 2.0.3
So far it appears to be compatible with Avast AIS.
Not much of a notable drain on system resources except when using the on-demand scan which can be scheduled to run through the Sypbot GUI using Windows Task Scheduler.
On my Dell Desktop with 4GB DDR3 RAM and a Athlon 240 processor a complete scan took under 18 minutes and it found a butch of items to quarantine that Avast, Malwarebytes, SAS and WD missed. Avast will not be able to scan the Spybot Quarantine folder so it needs to be excluded from Avast scans. Avast Memory Scan does not identify Spybot signatures as a virus.
I know there are not many Spybot fans here but I just wanted to give a heads up that the new Beta appears to be compatible with Avast, is much improved in speed and appears to be improved in identifying threats as evidenced by what it found that the others missed. Yes I know they could be FPs.
The new real time monitor appears not to negatively impact my systems performance. One final note. The Beta release does appear to have some bugs so use at your own risk. However none of those have caused any system problems so far.
Forgot:
The Malware definitions now automatically updated.
Also, the Immunization process now removes old and outdated items from the Protection list keeping the database size down a bit.