I haven't noticed any issues with Bookmark saving/editing. But what I have noticed which a lot of other people are experiencing at least based on what the Chrome subreddit is showing me, is every time I close my browser I get a pop up saying that Chrome did not shut down properly. It also fails to properly load my Adblock Plus extension properly and I have to re-load it manually, and I also can't remove it completely as it just comes back with the same error.
It might not be Avast, that's just speculation so far, as there are a number of people who have reported issues with Chrome who don't have Avast or AVG installed. The timing also doesn't quite add up with the Avast update being the culprit as this issue didn't start happening for a lot of people until four or five days ago and most of us (myself included) updated well before that time. That being said, it could have come from an Avast emergency update or UI update which can happen without a full program update. I don't mean to necessarily let Avast off the hook prematurely as it is interesting that uninstalling Avast fixes the issue for some people, but there are a lot of people reporting similar problems with Chrome without having Avast installed.
I'm also using Avast Free whereas a lot of people saying uninstalling Avast fixed their Chrome issue are referring to Avast Premium, so not sure if that makes the difference here.
UPDATE: I tried changing my Download location settings, and after restarting the browser in addition to the above mentioned errors, that download directory setting reverted back to what it was before. I wonder if some settings that are device specific will change while others that sync across other devices through your Google account (like bookmarks or Language settings) will remain.
UPDATE 2: Yep, I just changed a setting that syncs across devices (Turning Safe Browsing off and then back on with Chrome restarts in between), and that setting stayed change. It looks like the settings issue is affecting device-specific settings. For the people who are having issues saving bookmarks, are any of you using Chrome as a standalone browser with no Google account login?