I am the OP,and quite frankly people on this site just cannot answer a simple request,please just answer my request,and that will suffice my simple requirements, I am not interested in the details regarding having 2 virus programs or even 10,I am a big boy now,so, unless you can answer my question for me, dont answer with banal info
Thanks to all 
Although the suggestion to have only one active antivirus is adequate and pertinent, I think the OP wants a direct answer, even when he seems to have understood the suggestion.
@
willofaustralia, if I understood correctly, what you need is to add an "exception" rule (path) to Avast. That means that Avast won't bother to scan the specific locations.
Open Avast GUI -> "Real Time Shields" -> "File System Shield" -> "Expert Settings" (middle-right of the GUI) -> "Exclusions" -> "Add" -> "Browse..."
Then select the path where the MSE databases are located (or whichever location is giving you problems and you want to "except"). Note that you can select a specific file, or group of files or folders using "*" or "*.*" and symbols alike. This should add the specific path to the "exception list". Click "OK" to close Avast GUI.
If this "exception" is not enough, then open Avast GUI -> "Settings" (the one at the upper section of the GUI) -> "Exclusions" -> and repeat the procedure to add here the selected path.
BUT, the suggestion to use only one active antivirus is still very much valid. I am just trying to give you the method you could try, eventhough I completely agree with the one-AV-only suggestion.
Please come back with feedback, whichever the result you get.