One should also take in consideration PUP detection and blocking suspicious destinations like PHISHING sites,
just there where cybercriminal activities lure.
Windows Defender does not equal normal AV in these respects nor even has Google Safebrowsing grade protection.
See Pondus's response on this matter. So Windows Defender is even catching up here.
Of course one adds a good ad- and script blocker to the browser like uBlock Origin and uMatrix,
or MBAM alerts for certain content alerts.
Moreover I write this post inside the Avast Secure Browser and there is a reason for that too.
Windows Defender is not bad for the moments that your AV for one reason or another does not work,
for instance because of critical Window file's FPs, but not under normal conditions.
polonus