If my googling is right it is an Instant Messaging application, Tencent QQ.
http://en.wikipedia.org/wiki/QQTencent QQ, generally referred to as QQ, is the most popular free instant messaging computer program in Asia, and the world’s third most popular IM service [1]. It's users are mainly in China. The program is maintained by Tencent Holdings Limited (HKSE: 0700), owned in part by Naspers.[2] Since its entrance into Chinese households QQ quickly emerged as a modern cultural phenomenon, now being portrayed in popular culture. Aside from the chat program, QQ has also developed many subfeatures including games, pets, ringtone downloads, etc.
If correct and QQ is an Instant Messaging it isn't a supported IM Application in the avast Instant Messaging provider.
I assume that by your attempts to exclude some qq files or folder, that avast is alerting on some files used by QQ, is this correct ?
If so, What is the malware name, the infected file name, where was it found e.g. (malware name, C:\windows\system32\infected-file-name.xxx) ?
Check the avast! Log Viewer (right click the avast icon), Warning section, this contains information on all avast detections.
If you are trying to exclude files in the avast Program Settings, Exclusions and the Standard Shield, Customize, Advanced, Add - what is the path you are entering ?