I have the same error: Reached the end of the file (38)
This is only the second time that Avast! has reported anything unusual, the first being when I first installed it and it apparently found a couple of viruses in a Windows backup file. Also, it is about 8 hours and the first full scan since I installed Internet Explorer 8; I've only been using Firefox before now. Coincidence?
The problem files are in:
D:\System Volume Information\_restore<very long string of numbers and letters>A0139736.EXE|>[EMUL]|>_sfx_manifest_
as above but file A0139737
(it would be very useful if we could copy/paste from the scan results page!)
I can't find this directory, let alone the files, on my D:\ drive but I guess it might be in a partition, as a post above pointed out.
The "apply" button in the scan results is greyed out, so I can't delete or do anything else to these 2 files.
All I really need to know is if this is actually a security problem. I'm undecided about uninstalling (or trying to) IE8.